Journal: Scientific Reports

Article Title: Improving lung cancer pathological hyperspectral diagnosis through cell-level annotation refinement

doi: 10.1038/s41598-025-85678-9

Figure Lengend Snippet: Experimental apparatus photograph ( a ) and experimental setup schematic diagram ( b ) of the HMI collection system. Collimating lens - CL; Liquid crystal tunable filter - LCTF; Beam splitter - BS; Microscopic objective - MO; Pathological slides - PS; Tube lens - TL; Complementary metal oxide semiconductor - CMOS. Schematic diagram of the hyperspectral data cube ( c ). Each data cube consists of 67 spectral channels and 3088 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\times$$\end{document} 2064 pixels, with each pixel containing information from different spectral bands, with the red and green curves corresponding to the cell nucleus and cytoplasm.

Article Snippet: The physical diagram of the HMI system used in our experiments is shown in Fig. a, and the main instruments included a halogen light source (OSL2, 150W, 400-1600nm, Thorlabs Inc., New Jersey, USA), a Complementary Metal Oxide Semiconductor (CMOS) camera (acA3088-57um, Basler Inc., Arensberg, Germany), collimating lens set (AC254-030-AB/AC254-050-AB, Thorlabs Inc., New Jersey, USA), an objective lens (10 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\times$$\end{document} /0.25, Olympus, Tokyo, Japan) and a liquid crystal tunable filter (LCTF-V10, Wayho Technology Co.).

Techniques:

Journal: Scientific Reports

Article Title: Improving lung cancer pathological hyperspectral diagnosis through cell-level annotation refinement

doi: 10.1038/s41598-025-85678-9

Figure Lengend Snippet: The HMI system details in this study and some systems proposed in existing literature.

Article Snippet: The physical diagram of the HMI system used in our experiments is shown in Fig. a, and the main instruments included a halogen light source (OSL2, 150W, 400-1600nm, Thorlabs Inc., New Jersey, USA), a Complementary Metal Oxide Semiconductor (CMOS) camera (acA3088-57um, Basler Inc., Arensberg, Germany), collimating lens set (AC254-030-AB/AC254-050-AB, Thorlabs Inc., New Jersey, USA), an objective lens (10 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\times$$\end{document} /0.25, Olympus, Tokyo, Japan) and a liquid crystal tunable filter (LCTF-V10, Wayho Technology Co.).

Techniques: Microscopy